{"id":1665,"date":"2024-07-03T11:03:53","date_gmt":"2024-07-03T08:03:53","guid":{"rendered":"https:\/\/berru.org\/?p=1665"},"modified":"2024-07-03T11:03:53","modified_gmt":"2024-07-03T08:03:53","slug":"insanlar-kuyruklarini-nasil-kaybetti","status":"publish","type":"post","link":"https:\/\/berru.org\/index.php\/2024\/07\/03\/insanlar-kuyruklarini-nasil-kaybetti\/","title":{"rendered":"\u0130nsanlar Kuyruklar\u0131n\u0131 Nas\u0131l Kaybetti?"},"content":{"rendered":"

HABER MERKEZ\u0130-<\/strong> Bu ke\u015fif haftal\u0131k “Nature” dergisinin ba\u015f sayfas\u0131na ta\u015f\u0131nd\u0131. Nature dergisinin 29 \u015eubat 2024 tarihli say\u0131s\u0131n\u0131n kapa\u011f\u0131, insanlar\u0131n kuyruklar\u0131n\u0131 neden kaybettiklerini a\u00e7\u0131klayan genetik bir \u00e7al\u0131\u015fmaya odaklan\u0131yor.<\/p>\n

\u00d6nde gelen bilim dergisi, “maymunlar\u0131 insanlardan ay\u0131ran en \u00f6nemli evrimsel de\u011fi\u015fim\u201d olarak \u201ckuyru\u011fun ortadan kalkmas\u0131na\u201d dikkat \u00e7ekti.<\/p>\n

Haftal\u0131k derginin \u00f6n kapa\u011f\u0131nda foto\u011fraflanan iki sevimli boneli maka\u011f\u0131n (Macaca radiata) atalar\u0131n\u0131n aksine, insanlar ve goril, \u015fempanze ve orangutan gibi antropomorfik maymunlar\u0131n, kuyruk sokumunun bir kal\u0131nt\u0131s\u0131 oldu\u011fu bu uzant\u0131y\u0131 yakla\u015f\u0131k 25 milyon y\u0131l \u00f6nce kaybetti\u011fi belirtiliyor.<\/p>\n

Genetik\u00e7i Bo Xia ve ABD’deki New York \u00dcniversitesi’nden meslekta\u015flar\u0131, bu evrimsel olguya ilk kez genetik bir a\u00e7\u0131klama getirdiler. \u0130ngiliz dergisindeki bilimsel bir makalede ara\u015ft\u0131rmac\u0131lar, TBXT geninin kuyruk olu\u015fumunda rol oynad\u0131\u011f\u0131n\u0131 ilk olarak bu gene sahip olan maymunlar\u0131n genomlar\u0131n\u0131 olmayanlarla kar\u015f\u0131la\u015ft\u0131rarak tespit ettiklerini a\u00e7\u0131klad\u0131lar. Di\u011fer bir ifadeyle, ara\u015ft\u0131rmada maymunlarda ve insanlarda kuyruk kayb\u0131na tek bir transpozonun katk\u0131da bulunmu\u015f olabilece\u011fi ortaya konuluyor.<\/p>\n

Genomlar\u0131 olmayan maymunlarda, TBXT genine bir DNA par\u00e7as\u0131 eklendi\u011fi belirtiliyor. Bu eklemeden kaynaklanan genin yeni versiyonu art\u0131k embriyonik geli\u015fim s\u0131ras\u0131nda kuyruk olu\u015fumu i\u00e7in \u00e7ok \u00f6nemli olan proteini \u00fcretmiyor.<\/p>\n

Farelerde yap\u0131lan genetik modifikasyon deneyleri, bu proteinin kilit rol\u00fcn\u00fc do\u011fruluyor: Bu protein olmadan, k\u00fc\u00e7\u00fck kemirgenlerin kuyruklar\u0131 k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc ya da tamamen yok oldu\u011fu tespit edildi.<\/p>\n

Ge\u00e7mi\u015fte yap\u0131lan \u00e7al\u0131\u015fmalarda 100’den fazla gen \u00e7e\u015fitli omurgal\u0131 t\u00fcrlerinde kuyruk geli\u015fimiyle ili\u015fkilendirilmi\u015fti ve \u00e7al\u0131\u015fman\u0131n yazarlar\u0131 kuyruk kayb\u0131n\u0131n bunlardan bir veya daha fazlas\u0131n\u0131n DNA kodundaki de\u011fi\u015fiklikler (mutasyonlar) yoluyla meydana geldi\u011fini varsay\u0131yordu.<\/p>\n

Nature dergisindeki \u00e7al\u0131\u015fman\u0131n yazarlar\u0131na g\u00f6re, yeni \u00e7al\u0131\u015fma kuyruklardaki farkl\u0131l\u0131klar\u0131n TBXT mutasyonlar\u0131ndan de\u011fil, maymunlar\u0131n ve insanlar\u0131n atalar\u0131nda genin d\u00fczenleyici koduna AluY ad\u0131 verilen bir DNA par\u00e7ac\u0131\u011f\u0131n\u0131n eklenmesinden kaynakland\u0131\u011f\u0131n\u0131 ortaya koyuyor.<\/p>\n","protected":false},"excerpt":{"rendered":"

HABER MERKEZ\u0130- Bu ke\u015fif haftal\u0131k “Nature” dergisinin ba\u015f sayfas\u0131na ta\u015f\u0131nd\u0131. Nature dergisinin 29 \u015eubat 2024 tarihli say\u0131s\u0131n\u0131n kapa\u011f\u0131, insanlar\u0131n kuyruklar\u0131n\u0131 neden kaybettiklerini a\u00e7\u0131klayan genetik bir \u00e7al\u0131\u015fmaya odaklan\u0131yor. \u00d6nde gelen bilim dergisi, “maymunlar\u0131 insanlardan ay\u0131ran en \u00f6nemli evrimsel de\u011fi\u015fim\u201d olarak \u201ckuyru\u011fun ortadan kalkmas\u0131na\u201d dikkat \u00e7ekti. Haftal\u0131k derginin \u00f6n kapa\u011f\u0131nda foto\u011fraflanan iki sevimli boneli maka\u011f\u0131n (Macaca radiata) […]<\/p>\n","protected":false},"author":2,"featured_media":1666,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"","source_url":"","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"top","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"1","show_post_reading_time":"0","post_reading_time_wpm":"300","show_zoom_button":"0","zoom_button_out_step":"2","zoom_button_in_step":"3","show_post_tag":"1","show_prev_next_post":"1","show_popup_post":"1","number_popup_post":"1","show_author_box":"1","show_post_related":"0","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-500","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trendler","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"","hide":""},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_review":[],"enable_review":"0","type":"percentage","name":"","summary":"","brand":"","sku":"","good":[{"good_text":""}],"bad":[{"bad_text":""}],"score_override":"0","override_value":"","rating":[{"rating_text":"","rating_number":"10"}],"price":[{"shop":"","price":"","link":"","icon":""}],"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"jnews_post_split":{"enable_post_split":"0","post_split":[{"template":"1","tag":"h2","numbering":"asc","mode":"normal","first":"0","enable_toc":"0","toc_type":"normal"}]},"footnotes":""},"categories":[58],"tags":[],"class_list":["post-1665","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/berru.org\/wp-content\/uploads\/2024\/07\/maymun-1-1.jpg","_links":{"self":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1665","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/comments?post=1665"}],"version-history":[{"count":1,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1665\/revisions"}],"predecessor-version":[{"id":1667,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1665\/revisions\/1667"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/media\/1666"}],"wp:attachment":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/media?parent=1665"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/categories?post=1665"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/tags?post=1665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}