{"id":1647,"date":"2024-07-01T12:09:36","date_gmt":"2024-07-01T09:09:36","guid":{"rendered":"https:\/\/berru.org\/?p=1647"},"modified":"2024-07-01T12:09:36","modified_gmt":"2024-07-01T09:09:36","slug":"olurken-beynimizde-ne-oluyor","status":"publish","type":"post","link":"https:\/\/berru.org\/index.php\/2024\/07\/01\/olurken-beynimizde-ne-oluyor\/","title":{"rendered":"\u00d6l\u00fcrken Beynimizde Ne Oluyor?"},"content":{"rendered":"

HABER MERKEZ\u0130-<\/strong> Sinirbilimci Jimo Borjigin, “\u00f6lmenin ya\u015fam\u0131n \u00f6nemli bir par\u00e7as\u0131” olmas\u0131na ra\u011fmen \u00f6l\u00fcm an\u0131nda beyinde neler oldu\u011fu hakk\u0131nda “neredeyse hi\u00e7bir \u015fey” bilinmedi\u011fini fark etti\u011finde \u00e7ok \u015fa\u015f\u0131rm\u0131\u015f.<\/p>\n

Borjigin, yakla\u015f\u0131k 10 y\u0131l \u00f6nce farelerin beynindeki n\u00f6rokimyasal salg\u0131lar \u00fczerinde deney yaparken iki farenin \u00f6ld\u00fc\u011f\u00fcn\u00fc ve bu sayede tesad\u00fcfen beyinlerinin \u00f6l\u00fcm s\u00fcrecini g\u00f6zlemleyebildi\u011fini anlat\u0131yor.<\/p>\n

BBC Mundo’ya konu\u015fan Borjigin, “Farelerden bir tanesi a\u015f\u0131r\u0131 miktarda serotonin salg\u0131lad\u0131. Hal\u00fcsinasyon mu g\u00f6r\u00fcyordu acaba?” diyor ve serotoninin hal\u00fcsinasyonla ba\u011flant\u0131l\u0131 oldu\u011funa dikkat \u00e7ekiyor.<\/p>\n

Ruh halini d\u00fczenleyen bir hormon salg\u0131s\u0131 olan serotonini bu kadar y\u00fcksek d\u00fczeyde g\u00f6rmek Borjigin’de merak uyand\u0131rd\u0131:”Literat\u00fcr ara\u015ft\u0131rmas\u0131 yapmaya ba\u015flad\u0131m. \u00d6l\u00fcm s\u00fcreci hakk\u0131nda bu kadar az \u015fey bildi\u011fimizi \u00f6\u011frenince \u00e7ok \u015fa\u015f\u0131rd\u0131m.”<\/p>\n

Michigan \u00dcniversitesi’nde molek\u00fcler ve b\u00fct\u00fcnle\u015ftirici fizyoloji ve n\u00f6roloji alan\u0131nda do\u00e7ent olan Dr. Borjigin, o zamandan beri \u00f6l\u00fcm an\u0131nda beyinde neler oldu\u011funu inceliyor ve tespitlerinin sand\u0131\u011f\u0131m\u0131zdan farkl\u0131 oldu\u011funu s\u00f6yl\u00fcyor.<\/p>\n

\u00d6l\u00fcm\u00fcn tan\u0131m\u0131<\/h2>\n
\n

Borjigin, bilim d\u00fcnyas\u0131nda kalbi duran bir ki\u015finin \u00f6ld\u00fc\u011f\u00fcn\u00fcn varsay\u0131ld\u0131\u011f\u0131n\u0131, ancak bu s\u00fcre\u00e7te beyne de\u011fil kalbe odaklan\u0131ld\u0131\u011f\u0131n\u0131 s\u00f6yl\u00fcyor.<\/p>\n<\/div>\n

\n

“Bilimsel anlay\u0131\u015fa g\u00f6re beyin \u00e7al\u0131\u015fm\u0131yor gibi g\u00f6r\u00fcn\u00fcyor \u00e7\u00fcnk\u00fc ki\u015fiden tepki gelmiyor; konu\u015fam\u0131yor, ayakta duram\u0131yor, oturam\u0131yor.”<\/p>\n<\/div>\n

\n

Beynin \u00e7al\u0131\u015fabilmesi i\u00e7in \u00e7ok fazla oksijene ihtiyac\u0131 var. E\u011fer kalp kan pompalamazsa, oksijen de beyne ula\u015famaz.<\/p>\n<\/div>\n

\n

Borjigin, “Yani t\u00fcm y\u00fczeysel g\u00f6stergeler beynin art\u0131k \u00e7al\u0131\u015fmad\u0131\u011f\u0131na ya da en az\u0131ndan hiperaktif de\u011fil de hipoaktif oldu\u011funa i\u015faret ediyor” diyor.<\/p>\n<\/div>\n

\n

Beyin ‘hiper h\u0131zda’<\/h2>\n<\/div>\n
\n

Borjigin, ara\u015ft\u0131rma ekibiyle 2013 y\u0131l\u0131nda fareler \u00fczerinde yapt\u0131\u011f\u0131 bir \u00e7al\u0131\u015fmada hayvanlar\u0131n kalpleri durduktan sonra \u00e7e\u015fitli n\u00f6rotransmitterlerde yo\u011fun aktivite g\u00f6zlemlendi\u011fini anlat\u0131yor:<\/p>\n<\/div>\n

\n

“Serotonin 60 kat artarken kendinizi iyi hissetmenizi sa\u011flayan bir kimyasal olan dopamin 40 ila 60 kat artt\u0131. Kendinizi \u00e7ok uyan\u0131k hissetmenizi sa\u011flayan norepinefrin ise yakla\u015f\u0131k 100 kat artt\u0131.”<\/p>\n<\/div>\n

\n

Borjigin’e g\u00f6re hayvanlar canl\u0131yken bu kadar y\u00fcksek seviyeleri g\u00f6rmek imkans\u0131z.<\/p>\n<\/div>\n

\n

Ekip 2015 y\u0131l\u0131nda \u00f6lmek \u00fczere olan farelerin beyinleri \u00fczerinde bir \u00e7al\u0131\u015fma daha yapt\u0131:<\/p>\n<\/div>\n

\n

“Her iki durumda da beyin a\u015f\u0131r\u0131 hareket halinde, hiperaktif bir durumdayd\u0131.”<\/p>\n<\/div>\n

\n

Gama dalgalar\u0131<\/h2>\n
\n

Borjigin’in ekibi 2023 y\u0131l\u0131nda, ya\u015fam destek \u00fcnitesine ve beyin aktivitesini \u00f6l\u00e7en cihazlara ba\u011fl\u0131, \u00f6lmek \u00fczere olan d\u00f6rt ki\u015fi \u00fczerinde de bir \u00e7al\u0131\u015fma ger\u00e7ekle\u015ftirdi.<\/p>\n<\/div>\n

\n

Yak\u0131nlar\u0131n\u0131n karar\u0131yla bu ki\u015fileri hayatta tutan solunum cihazlar\u0131 kapat\u0131ld\u0131.<\/p>\n<\/div>\n

\n

Ara\u015ft\u0131rmac\u0131lar cihazlar\u0131n kapat\u0131lmas\u0131n\u0131n ard\u0131ndan hastalardan ikisinin beyninde y\u00fcksek d\u00fczeyde aktivite oldu\u011funu tespit etti. Bu, bili\u015fsel i\u015flevin bir g\u00f6stergesi.<\/p>\n<\/div>\n

\n

Hastalar\u0131n beyninde en h\u0131zl\u0131 beyin dalgalar\u0131 olan gama dalgalar\u0131 da tespit edildi. Gama dalgalar\u0131 karma\u015f\u0131k bilgi i\u015fleme ve haf\u0131za ile ba\u011flant\u0131l\u0131.<\/p>\n<\/div>\n

\n

Hastalardan birinde beynin her iki taraf\u0131ndaki temporal loblarda y\u00fcksek aktivite g\u00f6zlemlendi.<\/p>\n<\/div>\n

\n

Dr. Borjigin, sa\u011f taraftaki temporal lobun empatiyle ba\u011flant\u0131l\u0131 oldu\u011funa dikkat \u00e7ekiyor.<\/p>\n<\/div>\n

\n

\u00d6l\u00fcme yak\u0131n deneyimler<\/h2>\n
\n

\u00d6l\u00fcme yak\u0131n deneyimler ya\u015fayan baz\u0131 ki\u015filer hayatlar\u0131n\u0131n g\u00f6zlerinin \u00f6n\u00fcnden ge\u00e7ti\u011fini g\u00f6rebildiklerini veya \u00f6nemli anlar\u0131 hat\u0131rlayabildiklerini s\u00f6yl\u00fcyorlar.<\/p>\n<\/div>\n

\n

Bir\u00e7o\u011fu yo\u011fun bir \u0131\u015f\u0131k g\u00f6rd\u00fcklerini s\u00f6ylerken, baz\u0131lar\u0131 da beden d\u0131\u015f\u0131 deneyimler ya\u015fad\u0131klar\u0131n\u0131 payla\u015f\u0131yor.<\/p>\n<\/div>\n

\n

Peki Dr. Borjigin’in \u00e7al\u0131\u015fmalar\u0131nda g\u00f6zlemledi\u011fi hiperaktif beyin, baz\u0131 insanlar\u0131n \u00f6l\u00fcm\u00fcn e\u015fi\u011finde neden bu kadar yo\u011fun deneyimler ya\u015fad\u0131\u011f\u0131n\u0131 a\u00e7\u0131klayabilir mi?<\/p>\n<\/div>\n

\n

Borjigin, “Evet, bence a\u00e7\u0131kl\u0131yor” diyor ve devam ediyor:<\/p>\n<\/div>\n

\n

“Kalp krizinden kurtulanlar\u0131n en az %20-25’i beyaz bir \u0131\u015f\u0131k g\u00f6rd\u00fcklerini, bir \u015fey g\u00f6rd\u00fcklerini bildiriyor, bu da g\u00f6rsel korteksin aktif oldu\u011funu g\u00f6steriyor.”<\/p>\n<\/div>\n

\n

Ara\u015ft\u0131rmac\u0131lar, solunum cihazlar\u0131 kapat\u0131ld\u0131ktan sonra y\u00fcksek beyin aktivitesi g\u00f6zlenen iki hastan\u0131n durumunda, (bilin\u00e7li g\u00f6rmeyi sa\u011flayan) g\u00f6rsel kortekslerinin, “bu t\u00fcr g\u00f6rsel deneyimlerle ili\u015fkili olabilecek” yo\u011fun aktivite g\u00f6sterdi\u011fini s\u00f6yl\u00fcyor.<\/p>\n<\/div>\n

\n

Yeni bir anlay\u0131\u015f<\/h2>\n
\n

Dr. Borjigin, insanlar \u00fczerinde yapt\u0131\u011f\u0131 \u00e7al\u0131\u015fmalar\u0131n hen\u00fcz \u00e7ok az oldu\u011funu ve \u00f6l\u00fcm s\u0131ras\u0131nda beyinde neler oldu\u011funa dair daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 duyuldu\u011funu kabul ediyor.<\/p>\n<\/div>\n

\n

Ancak bu alanda 10 y\u0131ldan fazla s\u00fcren ara\u015ft\u0131rmalar\u0131ndan sonra Borjigin, kalp durmas\u0131 s\u0131ras\u0131nda beynin hiperaktif oldu\u011funu s\u00f6ylemenin m\u00fcmk\u00fcn oldu\u011funa inan\u0131yor.<\/p>\n<\/div>\n

\n

Peki oksijen alamad\u0131\u011f\u0131n\u0131 fark etti\u011finde beyinde ne oluyor?<\/p>\n<\/div>\n

\n

“Biz de bunu anlamaya \u00e7al\u0131\u015f\u0131yoruz. Bu konuda bilimsel literat\u00fcrde \u00e7ok az \u015fey var. Ger\u00e7ekten, hi\u00e7bir \u015fey bilinmiyor.”<\/p>\n<\/div>\n

\n

Borjigin k\u0131\u015f uykusundan bahsediyor ve insanlar ve fareler dahil baz\u0131 hayvanlar\u0131n oksijen eksikli\u011fiyle ba\u015fa \u00e7\u0131kmak i\u00e7in i\u00e7sel bir mekanizmaya sahip oldu\u011funa dikkat \u00e7ekiyor:<\/p>\n<\/div>\n

\n

“\u015eimdiye kadar beynin, kalp durmas\u0131n\u0131n masum bir seyircisi oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcyordu; kalp durdu\u011funda beynin de \u00f6ld\u00fc\u011f\u00fc.”<\/p>\n<\/div>\n

\n

Ancak Borjigin durumun b\u00f6yle olup olmad\u0131\u011f\u0131n\u0131 kesin olarak bilmedi\u011fimizde \u0131srar ediyor:<\/p>\n<\/div>\n

\n

“K\u0131\u015f uykusu, beynin asl\u0131nda bu zor durumdan ya da oksijen eksikli\u011finden kurtulacak mekanizmaya sahip oldu\u011funu g\u00f6steren \u00e7ok iyi \u00f6rneklerden biri. Ancak bunun ara\u015ft\u0131r\u0131lmas\u0131 gerekiyor.”<\/p>\n<\/div>\n

\n

Ke\u015ffedilecek \u00e7ok \u015fey var<\/h2>\n<\/div>\n
\n

Dr. Borjigin, kendisi ve ekibinin \u00e7al\u0131\u015fmalar\u0131ndaki bulgular\u0131n dev bir buzda\u011f\u0131n\u0131n sadece g\u00f6r\u00fcnen k\u0131sm\u0131 oldu\u011funu ve daha ke\u015ffedilecek \u00e7ok \u015fey oldu\u011funu d\u00fc\u015f\u00fcn\u00fcyor:<\/p>\n<\/div>\n

\n

“\u015eimdi soru \u015fu: \u00d6lmekte olan beyin niye daha aktif hale geliyor?” diyen Borjigin devam ediyor:<\/p>\n<\/div>\n

\n

“Anlamak, incelemek, ara\u015ft\u0131rmak ve \u00f6\u011frenmek i\u00e7in bir araya gelmemiz gerekiyor \u00e7\u00fcnk\u00fc \u00f6l\u00fcm mekanizmas\u0131n\u0131 anlamad\u0131\u011f\u0131m\u0131z i\u00e7in milyonlarca insana erken \u00f6l\u00fcm te\u015fhisi koyuyor olabiliriz.”<\/p>\n

Kaynak:BBC<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

HABER MERKEZ\u0130- Sinirbilimci Jimo Borjigin, “\u00f6lmenin ya\u015fam\u0131n \u00f6nemli bir par\u00e7as\u0131” olmas\u0131na ra\u011fmen \u00f6l\u00fcm an\u0131nda beyinde neler oldu\u011fu hakk\u0131nda “neredeyse hi\u00e7bir \u015fey” bilinmedi\u011fini fark etti\u011finde \u00e7ok \u015fa\u015f\u0131rm\u0131\u015f. Borjigin, yakla\u015f\u0131k 10 y\u0131l \u00f6nce farelerin beynindeki n\u00f6rokimyasal salg\u0131lar \u00fczerinde deney yaparken iki farenin \u00f6ld\u00fc\u011f\u00fcn\u00fc ve bu sayede tesad\u00fcfen beyinlerinin \u00f6l\u00fcm s\u00fcrecini g\u00f6zlemleyebildi\u011fini anlat\u0131yor. BBC Mundo’ya konu\u015fan Borjigin, “Farelerden […]<\/p>\n","protected":false},"author":2,"featured_media":1649,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"jnews-multi-image_gallery":[],"jnews_single_post":{"source_name":"","source_url":"","via_name":"","via_url":"","override_template":"0","override":[{"template":"1","single_blog_custom":"","parallax":"1","fullscreen":"1","layout":"right-sidebar","sidebar":"default-sidebar","second_sidebar":"default-sidebar","sticky_sidebar":"1","share_position":"top","share_float_style":"share-monocrhome","show_share_counter":"0","show_view_counter":"0","show_featured":"1","show_post_meta":"1","show_post_author":"0","show_post_author_image":"1","show_post_date":"1","post_date_format":"default","post_date_format_custom":"Y\/m\/d","show_post_category":"1","show_post_reading_time":"0","post_reading_time_wpm":"300","show_zoom_button":"0","zoom_button_out_step":"2","zoom_button_in_step":"3","show_post_tag":"1","show_prev_next_post":"1","show_popup_post":"1","number_popup_post":"1","show_author_box":"1","show_post_related":"0","show_inline_post_related":"0"}],"override_image_size":"0","image_override":[{"single_post_thumbnail_size":"crop-500","single_post_gallery_size":"crop-500"}],"trending_post":"0","trending_post_position":"meta","trending_post_label":"Trendler","sponsored_post":"0","sponsored_post_label":"Sponsored by","sponsored_post_name":"","sponsored_post_url":"","sponsored_post_logo_enable":"0","sponsored_post_logo":"","sponsored_post_desc":"","disable_ad":"0"},"jnews_primary_category":{"id":"","hide":""},"jnews_social_meta":{"fb_title":"","fb_description":"","fb_image":"","twitter_title":"","twitter_description":"","twitter_image":""},"jnews_review":[],"enable_review":"0","type":"percentage","name":"","summary":"","brand":"","sku":"","good":[{"good_text":""}],"bad":[{"bad_text":""}],"score_override":"0","override_value":"","rating":[{"rating_text":"","rating_number":"10"}],"price":[{"shop":"","price":"","link":"","icon":""}],"jnews_override_counter":{"override_view_counter":"0","view_counter_number":"0","override_share_counter":"0","share_counter_number":"0","override_like_counter":"0","like_counter_number":"0","override_dislike_counter":"0","dislike_counter_number":"0"},"jnews_post_split":{"enable_post_split":"0","post_split":[{"template":"1","tag":"h2","numbering":"asc","mode":"normal","first":"0","enable_toc":"0","toc_type":"normal"}]},"footnotes":""},"categories":[58],"tags":[],"class_list":["post-1647","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/berru.org\/wp-content\/uploads\/2024\/07\/8aab6680-3300-11ef-a044-9d4367d5b599.jpg.webp","_links":{"self":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/comments?post=1647"}],"version-history":[{"count":1,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1647\/revisions"}],"predecessor-version":[{"id":1650,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/posts\/1647\/revisions\/1650"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/media\/1649"}],"wp:attachment":[{"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/media?parent=1647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/categories?post=1647"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/berru.org\/index.php\/wp-json\/wp\/v2\/tags?post=1647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}